What drugs interact with Zoladex?
Most frequently checked interactions
- amlodipine.
- anastrozole.
- aspirin.
- atorvastatin.
- bicalutamide.
- exemestane.
- gabapentin.
- ibuprofen.
How long does it take for Zoladex 3.6 to start working?
After your first Zoladex implant, it takes 2 to 4 weeks for your hormone levels to drop. Many of Zoladex’s side effects, such as hot flashes, acne, and sexual problems, are related to this hormone level drop. As a result, you may notice most of Zoladex’s side effects starting within 2 to 4 weeks.
How long does Zoladex 10.8 mg last?
Zoladex 10.8 is a special preparation of goserelin acetate which is designed to work in the body for 12 to 13 weeks after each injection. Most people will need one injection for each 12 to 13 weeks of treatment.
What should be prescribed with goserelin?
Goserelin implant is used in combination with radiation therapy and other medications to treat localized prostate cancer and is used alone to treat the symptoms associated with advanced prostate cancer. It is also used to treat advanced breast cancer in certain women.
Can you take vitamins with Zoladex?
No interactions were found between Vitamin D3 and Zoladex.
Can I take ibuprofen with Zoladex?
Interactions between your drugs No interactions were found between ibuprofen and Zoladex.
How long does Zoladex 3.6 stay in your system?
After the pellet is injected, it slowly dissolves and releases Zoladex 3.6. Each pellet takes about 4 weeks (28 days) to dissolve completely. By four weeks, almost all the Zoladex 3.6 is gone and has been used by the body.
What is the difference between Lupron and Zoladex?
Zoladex contains the active drug goserelin. Lupron Depot contains the active drug leuprolide. Although they contain different active drugs, Zoladex and Lupron Depot work in the same way. They both block production of certain hormones, including estrogen and testosterone.
How do you take Zoladex 10.8 mg?
The Zoladex LA 10.8 mg Implant will be injected under the skin on your stomach every 12 weeks. This will be done by your doctor or nurse. It is important that you keep having Zoladex LA treatment, even if you are feeling well. Keep having this treatment until your doctor decides that it is time for you to stop.
What are the side effects of Zoladex 10.8 mg?
Common side effects of Zoladex 10.8 include:
- hot flashes (flushing)
- dizziness.
- headache.
- increased sweating.
- increased or decreased sexual interest.
- impotence.
- fewer erections than usual.
- trouble sleeping.
What is the half life of Zoladex?
Zoladex is poorly protein bound and has a serum elimination half-life of two to four hours in subjects with normal renal function. The half-life is increased in patients with impaired renal function. For the compound given in a 10.8 mg depot formulation every 12 weeks this change will not lead to any accumulation.
Can I take vitamin D with Zoladex?
Interactions between your drugs No interactions were found between Vitamin D3 and Zoladex. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Does Zoladex cause frequent urination?
This is a normal response by your body to this drug. This may cause new or worsening symptoms (such as increased pain, increased difficulty urinating in men) for the first few weeks.
How long do hot flushes last after Zoladex?
Hot flushes can last between 2 to 30 minutes. You may have a few a month or more often. The flushes usually last for a few months but for some people they carry on for longer. They can be disruptive and might make sleeping difficult.
Does Zoladex affect sleep?
nausea, diarrhea, sleep problems (insomnia), acne, or.
How often is Zoladex 10.8 mg given?
You should be given a Zoladex LA injection every 12 weeks. Always remind the doctor or nurse to set up an appointment for your next injection. If you are given an appointment for your next injection which is earlier or later than 12 weeks from your last injection, tell your doctor or nurse.
What is Zoladex LA 10.8 mg used for?
What Is Zoladex? Zoladex 10.8 (goserelin acetate implant) is a man-made form of a hormone used in men to treat symptoms of prostate cancer, and in women to treat breast cancer or endometriosis.
How long can you have Zoladex injections for?
To treat uterine fibroids, you should only have Zoladex for up to three months. To treat endometriosis, you should only have Zoladex for up to six months. To make the lining of your uterus thinner before an operation on your womb, you should only have Zoladex for one or two months (four or eight weeks).
How long does it take for Zoladex to start working?
Within three weeks of the first injection, your oestrogen will be lowered to a level similar to that of a post-menopausal woman and your periods will normally stop. This effect is temporary and will only last for as long as you’re having goserelin.
Does Zoladex weaken bones?
Zoladex can decrease bone mineral density, which may increase your risk of developing osteoporosis. This risk may be greater if you smoke, drink alcohol frequently, have a family history of osteoporosis, or use certain drugs such as seizure medications or steroids.
Can Zoladex cause UTI?
Initially, ZOLADEX, like other GnRH agonists, causes transient increases in serum levels of testosterone….Table 3 : TREATMENT RECEIVED.
| ADVERSE EVENT | ZOLADEX (n=242) % | ORCHIECTOMY (n=254) % |
|---|---|---|
| Decreased Erections | 18 | 16 |
| Lower Urinary Tract Symptoms | 13 | 8 |
| Lethargy | 8 | 4 |
Does Zoladex make you feel tired?
Tell your doctor right away if you have any serious side effects, including: vaginal burning/pain, pain during sex (in women), breast pain/tenderness, new/worsening bone pain, new broken bone, burning feeling in feet/toes, swelling of the ankles/feet, unusual tiredness, signs of kidney problems (such as change in the …
How is Zoladex 10.8 mg given?
Zoladex® 10.8mg can only be administered by a doctor or nurse. The implant is a very small pellet that is given by a special needle and syringe known as SafeSystemTM. The injection will not hurt very much. The pellet is designed to slowly release the medicine into your body over three months.