What are the differential diagnosis for scleroderma?
Usually, five entities are differentiated: linear circumscript scleroderma, plaque-type morphea, bullous morphea, generalized morphea and deep morphea [22]. In these diseases usually no RP, ANA or organ involvement are found. Clinically characteristics of morphea are one or more circumscribed oval plaques.
What causes scleredema?
Febrile illness with streptococcal infections [8, 9] : An upper respiratory tract infection (typically pharyngitis) is the most common cause of scleredema in patients with type 1 scleredema. Scleredema following scabies infestation, as a result of superinfection with Streptococcus, has been reported.
Can a blood test detect scleroderma?
A blood test alone cannot diagnose scleroderma. Depending on the clinical situation, additional tests may be done, such as: Pulmonary function tests or breathing tests to measure how well the lungs are working. CT chest scan may also be ordered to evaluate the extent of lung involvement.
What is the difference between Scleredema and scleroderma?
Scleredema is differentiated from scleroderma by the presence of mucin and the lack of destruction of skin adnexa.
How do you confirm scleroderma?
To diagnose scleroderma, a doctor usually begins by asking you about your symptoms, health, and medical history. The doctor will also examine your skin for signs of hardening and thickening. If you have hard, thickened skin, a dermatologist may perform a skin biopsy to help diagnose you.
What is CREST syndrome?
CREST syndrome is a complicated disease that affects several parts of the body. It can cause the thickening and/or hardening of the skin and internal organs. CREST is the acronym used to describe a number of conditions within the category of systemic sclerosis (scleroderma).
Is scleroderma and morphea the same thing?
Morphea, also known as localized scleroderma, is a condition which causes hardening and discoloration of the skin. It is thought to be isolated to the skin without internal organ involvement as seen in systemic sclerosis (commonly known as scleroderma).