What is a positive CA 125?
If your CA 125 level is higher than expected, you may have a condition that isn’t cancerous, or the test result could mean that you have ovarian, endometrial, peritoneal or fallopian tube cancer. Your provider may recommend other tests and procedures to determine your diagnosis.
How do I interpret CA 125 results?
How do I interpret my test results for certain types of ovarian cancer? The normal range of a CA 125 is less than 35. If your CA 125 is higher than 35, your doctor will consider your symptoms, the results from your scans (such as CT scan) if you had them done and your clinic examination.
What cancer marker is CA 125?
A test for a tumor marker called HE4 may be done along with a CA-125 blood test. An HE4 test is most often used to monitor women who have been treated for a common type of ovarian cancer called epithelial ovarian cancer.
What is CA 125 diagnosis level?
Generally speaking, the normal range of CA-125 is considered to be 0-35 units/mL, while a level above 35 units/mL is considered to be a high CA-125 level.
Is a CA-125 blood test accurate?
A CA125 test is not reliable enough to be used on its own in ovarian cancer. The level of CA125 can also be raised due to non-cancerous conditions and other types of cancer. Sometimes in early ovarian cancer, CA125 levels may be normal. Your GP or hospital doctor will arrange for you to have a CA125 blood test.
How is ovarian cancer detected?
The 2 tests used most often (in addition to a complete pelvic exam) to screen for ovarian cancer are transvaginal ultrasound (TVUS) and the CA-125 blood test. TVUS (transvaginal ultrasound) is a test that uses sound waves to look at the uterus, fallopian tubes, and ovaries by putting an ultrasound wand into the vagina.
What is a normal cancer marker for ovarian cancer?
Cancer antigen 125 (CA 125) is the only tumor marker recommended for clinical use in the diagnosis and management of ovarian cancer. The reference range of CA 125 is 0-35 units/mL (0-35 kU/L).
Can CA-125 detect lymphoma?
In conclusion, for patients with NHL, high levels of CA 125 were associated with B-symptoms, advanced stage, bulky disease, abdominal, and serosal involvement. Therefore, CA 125 might be used as a marker to predict prognosis and to detect advanced disease in NHL.
How is Stage 1 ovarian cancer diagnosed?
Diagnosis and treatment of ovarian cancer stage 1 To diagnose possible ovarian cancer, your doctor will likely recommend a pelvic exam. Because small tumors in the ovaries may be difficult to detect, other tests may include: transvaginal ultrasound. blood test.
Is CA-125 only for ovarian cancer?
The cancer antigen 125 (CA 125) blood test isn’t recommended for women with an average risk of ovarian cancer. While women with ovarian cancer often have an elevated level of CA 125 , an elevated CA 125 level doesn’t always mean you have ovarian cancer.
Can you still have ovarian cancer if CA-125 is normal?
A normal CA125 test cannot be used to rule out ovarian cancer. Some women with ovarian tumours never have an elevated CA125, and about half of women with early-stage tumours have a CA125 level in the normal range. So it’s possible to have ovarian cancer and a normal CA125 result.
What is normal tumor marker range?
Normal range: < 2.5 ng/ml. Normal range may vary somewhat depending on the brand of assay used. Levels > 10 ng/ml suggest extensive disease and levels > 20 ng/ml suggest metastatic disease.
Can CA 125 detect leukemia?
CA 125 was not detectable in leukemic cell extracts nor in the supernatant fluid of primary cultures. Conclusions: These results indicate that leukemic cells were unable to produce CA 125 and suggest that its elevation in the serum is likely due to a serosal inflammatory reaction caused by the leukemic infiltration.
How accurate is the CA 125 blood test?
Results: Using a CA125 cutoff of 30 U/mL, an overall sensitivity of 94.8% (96.6% specificity) was obtained when comparing malignancies versus healthy postmenopausal controls, whereas a cutoff of 65 U/mL provided a sensitivity of 83.9% (99.6% specificity).