How do you get rid of a giant cell tumor of the tendon sheath?
Often, partial excision of the joint capsule or tendon sheath is necessary for complete removal of the tumor. Meticulous dissection and exploration are essential because satellite lesions are common.
What is Tenosynovial giant cell Tumour?
A type of rare tumor that forms in the synovium (tissue that lines the joints), the tendon sheath (tissue that covers the tendons), or the bursa (a fluid-filled sac between bones, tendons, and muscles).
What is giant cell tumor of tendon sheath?
Giant cell tumor of tendon sheath (GCTTS) is characterized by diffuse proliferation of synovial-like cells and multinucleated giant cells along tendon sheaths. This benign tumor typically presents in the third to fourth decade of life and is exceeding rare in children.
How is TGCT diagnosed?
To diagnose TGCT, your doctor will likely perform a thorough physical exam and order imaging scans, such as a computerized tomography (CT) scan or magnetic resonance imaging (MRI), to look at the affected joint and the surrounding area, says Scharschmidt.
Can giant cell tumors grow back?
Tumors that can’t be removed surgically can often be controlled and sometimes destroyed with radiation therapy. Giant cell tumors can come back. Follow-up with your healthcare provider may be required for several years.
What percentage of giant cell tumor is malignant?
The most recent data from the 4 large GCTB patient series showed that the frequency of malignancy was 1.1% to 11.3% (Table 1).
Is TGCT a sarcoma?
Tenosynovial giant cell tumors (TGCTs) are a group of rare, benign tumors that involve the synovium, bursae and tendon sheath. Synovium is the thin layer of tissue or membrane that covers the inner surface of the joint spaces and the bursae and tendon sheaths.
Is TGCT a type of sarcoma?
Malignant TGCT is, therefore, still an orphan disease with unmet medical needs. Better understand of biological and molecular characteristics of this subtype of sarcoma and more clinical trials are needed in order to develop new therapies able to efficiently target specific pathways.
Is there a cure for giant cell tumors?
How often do giant cell tumors come back?
Depending on the type of surgical procedure and local presentation of the tumor, the recurrence rate of GCTB could range from 2.5% to 45% [5], [6]. Patients treated with intralesional curettage were reported to have higher recurrence rate than those undergoing wide resection of the tumor [7], [8].
Can giant cell tumor be cured?
The goal for treatment of a giant cell tumor is to remove the tumor and prevent damage to the affected bone. Tumors that can’t be removed surgically can often be controlled and sometimes destroyed with radiation therapy. Giant cell tumors can come back.
Can giant cell tumor go away?
How many people have TGCT?
TGCTs are rare and researchers don’t know exactly how many people are diagnosed with TGCT each year. However, a study done in the Netherlands was used to calculate the worldwide incidence. Globally, it is estimated that 43 people out of every million are diagnosed with TGCT, localized and diffuse forms, each year (5).