Is Morphea scleroderma fatal?
Pansclerotic morphea can be localized to relatively small areas of the body or can involve large areas of the body. Severe cases of pansclerotic morphea can produce long-term disability and on rare occasion have resulted in death.
How fast does morphea progress?
Superficial circumscribed morphea is a self-limited condition that tends to slowly involute with time; the duration of disease activity of each individual lesion averages 3-5 years; however, patients tend to develop new lesions over their lifetimes.
Does scleroderma affect life expectancy?
In general, patients with limited scleroderma have a normal life expectancy. Some have problems with their GI tract, especially heartburn; severe Raynaud’s and musculoskeletal pain; and a small subset can develop pulmonary hypertension that can be life-threatening.
Is morphea serious?
Morphea is a rare skin condition that will usually only affect the appearance of the skin and will go away without treatment. However, in more severe cases, morphea can cause mobility issues or deformities. In children, morphea can cause eye damage and problems with limb growth and movement.
How do you stop the spread of morphea?
For severe or widespread morphea, your doctor may prescribe an immunosuppressive medication, such as oral methotrexate (Trexall), corticosteroid pills or both. Or your doctor may suggest hydroxychloroquine (Plaquenil) or mycophenolate mofetil. Each of these drugs has potential side effects.
How does scleroderma lead to death?
Most scleroderma experts believe that, currently, the most frequent cause of death is pulmonary involvement, either interstitial lung disease or pulmonary arterial hypertension (PAH).
What is the best treatment for morphea?
Can morphea affect internal organs?
Morphea predominately affects your skin. It doesn’t involve your internal organs. In most cases, it resolves on its own, but you can experience a relapse. More severe forms can lead to cosmetic deformities, and it occasionally affects the muscle, joints, or bone.
What can trigger morphea?
The cause of morphea is unknown. It may be caused by an unusual reaction of your immune system. In people at increased risk of morphea, it could be triggered by injury to the affected area, medications, chemical toxins, an infection or radiation therapy. The condition isn’t contagious.
What type of scleroderma is fatal?
It is the most fatal of all the rheumatologic diseases. Systemic scleroderma is very unpredictable although most cases can be classified into one of four different general patterns of disease (see Classification).
What causes morphea to flare up?
Morphea may be triggered by radiation therapy, repeated trauma to your skin, environmental exposure, or an infection. Morphea isn’t contagious, so you can’t get it from or spread it by touching someone else.
What are the most rare autoimmune diseases?
10 Rare Autoimmune Diseases
- Kawasaki disease.
- Mixed connective tissue disease (MCTD)
- Myasthenia gravis.
- Paroxysmal nocturnal hemoglobinuria (PNH)
- POEMS syndrome.
- Retroperitoneal fibrosis.
- Scleroderma.
- Thyroid eye disease.
What is the number one autoimmune disease?
Autoimmune Disease Basics The most common autoimmune diseases in women are: Rheumatoid arthritis, a form of arthritis that attacks the joints. Psoriasis, a condition marked by thick, scaly patches of skin. Psoriatic arthritis, a type of arthritis affecting some people with psoriasis.
Can a person have 2 autoimmune diseases?
For people who have more than one diagnosed autoimmune disease, it’s called polyautoimmunity. The combination of three or more diagnosed autoimmune disorders in one person is called Multiple Autoimmune Syndrome (MAS).
What is the most rare autoimmune disease?
Asherson’s syndrome is an extremely rare autoimmune disorder characterized by the development, over a period of hours, days or weeks, of rapidly progressive blood clots affecting multiple organ systems of the body.