When are alpha-glucosidase inhibitors used?
Alpha-glucosidase inhibitors are used to establish greater glycemic control over hyperglycemia in diabetes mellitus type 2, particularly with regard to postprandial hyperglycemia.
Is acarbose an alpha-glucosidase inhibitor?
Acarbose, an alpha-glucosidase inhibitor, delays absorption of carbohydrate in the gut, thereby lowering postprandial glucose levels.
What are alpha-glucosidase enzymes?
Glucosidase enzymes catalyze hydrolysis of starch to simple sugars. In humans, these enzymes aid digestion of dietary carbohydrates and starches to produce glucose for intestinal absorption, which in turn, leads to increase in blood glucose levels.
Is acarbose and Voglibose same?
The mean change in SMBG levels 1 hr after dinner in acarbose group was larger than in voglibose group. Based on these results, both drugs were regarded to have similar effects on glycemic control. However, the effects of acarbose on postprandial glucose were slightly superior to those of voglibose.
What is the function of Voglibose?
Voglibose is an alpha-glucosidase inhibitor used for lowering post-prandial blood glucose levels in people with diabetes mellitus. It is made in India by Ranbaxy Labs and sold under the trade name Volix.
What are pioglitazone and rosiglitazone?
Abstract. Rosiglitazone and pioglitazone are two new additions to the therapeutic options for the treatment of type 2 diabetes mellitus. These agents differ from our current therapies in their mode of action.
What is another name for dapagliflozin?
Dapagliflozin is used with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus (not for type 1 diabetes).
What is gliclazide used for?
Gliclazide is one of a group of medicines called sulfonylureas that are used to lower the blood sugar level. Gliclazide tablets are used to treat maturity onset diabetes in patients that is not controlled by diet alone. They are not for use in children or in patients with diabetes requiring insulin.
What is another name for gliclazide?
Brand names: Dacadis, Diamicron, Edicil, Glydex, Laaglyda, Lamzarin, Nazdol, Vamju, Ziclaseg and Zicron.
Which is better voglibose or acarbose?
What class of drug is glibenclamide?
Glibenclamide is an adopted name for glyburide, a member of the sulfonylurea class of drugs, which are clinically used as an oral hypoglycemic agent for the treatment of diabetes (Fig. 7.8). These drugs act by inhibiting KATP sulfonylurea receptor 1 channels (Sur1-Kir6.
What are GLP 1 drugs?
GLP-1 receptor agonists are a type of non-insulin medication that is used in combination with diet and exercise to help treat type 2 diabetes.
Is voglibose and glimepiride?
Glimepiride + Metformin + Voglibose is a combination of three antidiabetic medicines: Glimepiride, metformin and voglibose. They work by different mechanisms to provide better control of blood sugar when single or dual therapy is not effective.
Which is better vildagliptin vs voglibose?
Gastrointestinal AEs were significantly lower with vildagliptin compared with that of the voglibose (18.6 vs. 32.8%; p = 0.002). Conclusions: Vildagliptin (50 mg bid) showed superior efficacy and better tolerability compared with voglibose in Japanese patients with T2D.
Which drug is sulfonylurea?
Common Sulfonylureas Some commonly prescribed sulfonylureas include: DiaBeta, Glynase, or Micronase (glyburide or glibenclamide) Amaryl (glimepiride) Diabinese (chlorpropamide)
What class of drug is pioglitazone?
Pioglitazone is in a class of medications called thiazolidinediones. It works by increasing the body’s sensitivity to insulin, a natural substance that helps control blood sugar levels.
What is rivaroxaban used for?
Rivaroxaban: a medicine to help prevent blood clots – NHS.