Is there a cure for follicular Mucinosis?
Follicular mucinosis is suggested to be a localized form of cutaneous T-cell lymphoma. There exists no treatment of choice for follicular mucinosis.
What is follicular Mucinosis?
Follicular mucinosis is a rare cutaneous mucinosis characterized by accumulation of mucin at the external root sheath and sebaceous glands . It manifests clinically as follicular papules distributed on the trunk, proximal limbs, scalp, and face; it may also exist as indurated plaques .
How common is follicular Mucinosis?
Follicular mucinosis is a rare disorder. The primary form occurs in children and young adults. In the absence of other disorders, it commonly shows localized lesions of the face, head and neck that have a tendency to resolve within two months to two years.
Is follicular Mucinosis itchy?
The mucin (gelatinous clear material) may ooze from these pores, especially if the area is touched or squeezed. There is usually loss of hair in the affected areas, sometimes accompanied by scarring. The skin lesions may be itchy.
What causes mucinosis?
The cause of the condition is unknown, but it is commonly associated with monoclonal gammopathy. It has also been reported in association with bone marrow cancers as well HIV infection, hepatitis C, exposure to toxic oil and contaminated L-tryptophan.
What does mucinosis look like?
Typically there are pink papules (small bumps) or plaques (larger raised or thickened areas of skin) with prominent pores which are the hair follicle openings. The mucin (gelatinous clear material) may ooze from these pores, especially if the area is touched or squeezed.
How is mucinosis treated?
Plaquelike cutaneous mucinosis treatments are mostly based on case reports. Antimalarial drugs and topical or systemic corticosteroids are the most frequently used.
What does follicular Mucinosis look like?
Is Focal mucinosis benign?
Solitary cutaneous focal mucinosis is a reactive benign process that has not typically been associated with systemic conditions [2-11]. In contrast, various medical conditions have been found in patients with diffuse mucinoses or multiple cutaneous focal mucinosis [12-16].
What causes focal Mucinosis?
Multiple cutaneous focal mucinosis can occur as an idiopathic condition; however, several of these individuals have a mucin-associated systemic disease. The associated systemic diseases include Birt-Hogg-Dube syndrome, scleroderma, scleromyxedema, systemic lupus erythematous, and thyroid disease.
Is Focal Mucinosis benign?
What is follicular mucinosis?
Abstract Follicular mucinosis is an uncommon inflammatory disorder that characteristically presents as follicular papules and/or indurated plaques. The face, neck, and scalp are the most frequently affected sites, although lesions may occur on any site of the body.
Does hydroxychloroquine work for rheumatoid arthritis?
Originally, hydroxychloroquine was used to prevent and treat malaria and was considered very effective. Now it is generally used for rheumatoid arthritis, but it has also been shown to work well for juvenile arthritis, some lupus symptoms, and other types of autoimmune conditions.
What is hydroxychloroquine used for?
Being able to stop joint damage can lessen pain and mean a better quality of life. Hydroxychloroquine is one of the medications that can be a valuable part of your treatment plan. What Conditions Does This Treat?
What is the pathophysiology of mucin accumulation in follicles?
Accumulation of mucin, which is composed of hyaluronate and sulfated glycosaminoglycans, in the follicle results in disruption of cellular attachments and destruction of the pilosebaceous subunit. With loss of the follicle, alopecia may be evident clinically.