What causes testicular choriocarcinoma?
The syndrome most often develops shortly after the initiation of chemotherapy, but cases of choriocarcinoma syndrome as the initial presentation of testicular cancer have been reported. The syndrome is characterized by hemorrhage from metastases and is characterized by acute hemorrhage from metastates.
What is testicular choriocarcinoma?
Introduction. Pure testicular choriocarcinoma is a non-seminomatous germ cell tumor (NSGCT) and is the rarest and most aggressive form of testicular cancer. Nearly all choriocarcinomas can be classified as either pure choriocarcinoma or as a component of a mixed germ cell tumor.
What is testicular Teratocarcinoma?
Testicular teratoma is a neoplasm derived from germ cells of the testicle. It can display diverse biological behavior with an aggressive nature at times, and therefore it must be promptly diagnosed and treated.
How does choriocarcinoma occur in males?
Choriocarcinoma in males commonly develops in the gonads (ie, testes). In some cases, extragonadal choriocarcinoma occurs in midline locations, such as the mediastinum, retroperitoneum and pineal gland, with rare cases reported in the parenchymal organs, such as the lungs, gastrointestinal tract and breast.
Is testicular choriocarcinoma curable?
Severe Complications in Testicular Germ Cell Tumors: The Choriocarcinoma Syndrome. Testicular germ cell tumors (TGCTs) represent the most common solid tumor in young men and is a model of curable cancer. The effectiveness of cisplatin-based chemotherapy secures more than 95% of patients’ 5-years survival rate.
What is the difference between teratoma and teratocarcinoma?
Teratocarcinomas are malignant tumors and may cause death due to invasion and metastasis if left untreated. A more correct term for the experimental tissue masses formed by human ES cells is mature teratomas.
What is seminoma and nonseminoma?
Seminomas are very sensitive to radiation therapy. Nonseminoma: This more common type of testicular cancer tends to grow more quickly than seminomas. Nonseminoma tumors are often made up of more than one type of cell, and are identified according to these different cell types: Choriocarcinoma (rare) Embryonal carcinoma.
How common is testicular choriocarcinoma?
Choriocarcinoma is the rarest subtype of germ cell malignancy with pure examples representing under 1% of the total number of NSGCT, while 7–8% of testicular tumors contain a choriocarcinoma component (15).
Can males have choriocarcinoma?
Primary choriocarcinoma (PCC) is a rare malignancy that can occur in both men and women. In men, the most common primary site is the testis. When the primary tumor is extragonadal, it can occur in the mediastinum,2 retroperitoneum,3 lung,4 brain,5 or digestive tract.
Is Stage 4 choriocarcinoma curable?
Fortunately, most women who are found to have choriocarcinoma can be cured; treatment with a combination of chemotherapy agents such as etoposide, methotrexate, actinomycin D, cyclophosphamide and vincristine (EMA-CO) is found to be very effective at achieving remission.
What are teratocarcinoma cells?
Teratocarcinoma is a form of malignant germ cell tumor that occurs in both animals and humans. These tumors comprise an undifferentiated embryonal carcinoma (EC) component and differentiated derivatives that can include all three germ layers.
What is Teratocarcinosarcoma?
Sinonasal teratocarcinosarcoma is a rare tumor of nasal cavity and of uncertain histogenesis.[1,2] Almost all cases are found in adults with a significant male predominance.[3] Histogenetically, this tumor is unlikely to be of germ cell origin but probably arises from a primitive cell in the olfactory membrane that not …
What is better seminoma or nonseminoma?
Seminomas are very sensitive to radiation therapy. Nonseminoma: This more common type of testicular cancer tends to grow more quickly than seminomas. Nonseminoma tumors are often made up of more than one type of cell, and are identified according to these different cell types: Choriocarcinoma (rare)
Is Testicular choriocarcinoma curable?
Can Stage 4 choriocarcinoma be cured?
What is Sinonasal Teratocarcinosarcoma?
Sinonasal teratocarcinosarcoma is an extremely rare malignant tumor arising in the sinonasal tract, having combined histological features of teratoma and carcinosarcoma. Here, we are presenting a case of sinonasal teratocarcinosarcoma in a 28-year-old male patient.