What does toremifene do to you?
Toremifene is in a class of medications called nonsteroidal antiestrogens. It works by blocking the activity of estrogen (a female hormone) in the breast. This may stop the growth of some breast tumors that need estrogen to grow.
What is the difference between tamoxifen and toremifene?
Methods: Toremifene is structurally similar to tamoxifen, differing only by a single chlorine atom, and has a similar pharmacologic profile. The major difference between the two compounds is in the preclinical activity; chronic, high-dose tamoxifen is hepatocarcinogenic in the rat, whereas toremifene is not.
Is toremifene a type of chemotherapy?
Fareston (toremifene citrate) is an estrogen agonist/antagonist that blocks estrogen from reaching cancer cells used to slow the growth of metastatic breast cancer (cancer that has spread from the original tumor). Unlike chemotherapy, Fareston does not actually destroy cancer cells.
How much toremifene should I take?
For breast cancer: Adults—60 milligrams (mg) once a day. Children—Use is not recommended.
Is toremifene a SERM?
Selective estrogen receptor modulators (SERMs), including tamoxifen and toremifene, are widely adjunctively used in breast and prostate cancer.
Does tamoxifen increase LH and FSH?
Abstract. The administration of tamoxifen, 20 mg/day for 10 days, to normal males produced a moderate increase in luteinizing hormone (LH), follicle-stimulating hormone (FSH), testosterone, and estradiol levels, comparable to the effect of 150 mg of clomiphene citrate (Clomid).
What are the side effects of tamoxifen?
Tamoxifen may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- increased bone or tumor pain.
- pain or reddening around the tumor site.
- hot flashes.
- nausea.
- excessive tiredness.
- dizziness.
- depression.
- headache.
Does toremifene increase testosterone?
Toremifene administration resulted in a significant increase in FSH, testosterone, SHBG, and inhibin B levels, as well as in sperm concentration, percentage motility and normal sperm forms.
What are the side effects of Torsemide?
This medication may cause dehydration and electrolyte imbalance. Tell your doctor right away if you have any of these unlikely but serious side effects: muscle cramps, weakness, unusual tiredness, confusion, severe dizziness, fainting, drowsiness, unusual dry mouth/thirst, nausea, vomiting, fast/irregular heartbeat.
How do you pronounce toremifene?
Pronunciation : tore-EM-i-feen Latest prescription information about Toremifene.
How quickly does tamoxifen increase testosterone?
The administration of tamoxifen, 20 mg/day for 10 days, to normal males produced a moderate increase in luteinizing hormone (LH), follicle-stimulating hormone (FSH), testosterone, and estradiol levels, comparable to the effect of 150 mg of clomiphene citrate (Clomid).
Does Nolvadex raise estrogen?
While primarily viewed as an anti-estrogen, Nolvadex also has retention ability to act as estrogen, specifically in the liver. Many forms of breast cancer actually feed off estrogen when it attaches help the receptors in the chest.
What does Nolvadex do PCT?
Nolvadex is the top dog at reducing oestrogen levels, helping to bring that precious endogenous testosterone back to a stable, healthy level. Likewise, supplements, such as phosphatidylserine and acetyl-l-carnitine, may also be used within the PCT to lower cortisol levels.
Can torsemide increase creatinine levels?
In hypertensive patients who received 10 mg of Torsemide daily for 6 weeks, the mean increase in blood urea nitrogen was 1.8 mg/dL (0.6 mmol/L), the mean increase in serum creatinine was 0.05 mg/dL (4 mmol/L), and the mean increase in serum uric acid was 1.2 mg/dL (70 mmol/L).